Alfa Chemistry provides high-performance polyethylene glycol-modified black phosphorus nanosheet dispersions (PEG-BPNSs), engineered to overcome the stability and biocompatibility challenges typically associated with black phosphorus nanosheets (BPNSs). Surface modification with polyethylene glycol (PEG) significantly enhances the material's functionality, making it ideal for a wide range of advanced research and biomedical applications.

Product Highlights
- Improved Oxidative Stability: PEGylation effectively protects black phosphorus nanosheets from rapid oxidation, enabling longer shelf life and consistent performance in experimental and therapeutic settings.
- Enhanced Biocompatibility: The PEG coating reduces cytotoxicity and improves biological compatibility, supporting safe use in drug delivery, bioimaging, and in vivo applications.
- Excellent Dispersibility: This dispersion exhibits stable, uniform suspension in polar solvents such as water and normal saline, allowing for easy handling and reliable performance across diverse protocols.
Specifications
| Catalog Number | Parameters | Packaging | Lateral Length | Thickness |
| GH-GLM031 | C: 0.5 mg/mL, Water | 10 mL | 100 nm–5 μm | 1–10 layers |
| GH-GLM032 | C: 0.5 mg/mL, Water | 20 mL | 100 nm–5 μm | 1–10 layers |
| GH-GLM033 | C: 0.5 mg/mL, Water | 15 mL | 100 nm–5 μm | 1–10 layers |
| GH-GLM034 | C: 0.5 mg/mL, Water | 25 mL | 100 nm–5 μm | 1–10 layers |
| GH-GLM035 | C: 0.5 mg/mL, Normal Saline | 10 mL | 100 nm–5 μm | 1–10 layers |
| GH-GLM036 | C: 0.5 mg/mL, Normal Saline | 15 mL | 100 nm–5 μm | 1–10 layers |
| GH-GLM037 | C: 1.0 mg/mL, Water | 50 mL | 100 nm–5 μm | 1–10 layers |
Application Areas
- Targeted Drug Delivery
PEG-BPNSs can serve as nanocarriers for therapeutic agents, enabling controlled release and targeted delivery. This can help enhance drug efficacy and reduce systemic side effects.
- Photothermal Cancer Therapy
Black phosphorus nanosheets exhibit excellent photothermal conversion efficiency. When irradiated with near-infrared light, they generate localized heat to destroy tumor cells. PEG modification further improves circulation time and therapeutic precision.
- Bioimaging
Due to their excellent dispersibility and reduced toxicity, PEG-BPNSs are well-suited for in vivo imaging techniques, including fluorescence and magnetic resonance imaging (MRI). In one study, researchers used PEG-modified nanosheets loaded with anticancer drugs to achieve high treatment efficiency with minimal impact on surrounding healthy tissue.
With optimized stability, safety, and performance, modified black phosphorus nanosheet dispersion is a powerful tool for researchers in nanomedicine, drug delivery, and imaging. Alfa Chemistry supports both standard and custom orders to meet the unique needs of your research.
Contact us today to learn more or request a quote.

